Neuroscience of Addictions – The Brain Chemistry of Alcohol Alcohol is one of the most commonly abused substances, and certainly one of the best studied. However, alcohol is non-specific in its binding targets, making it difficult to fully understand the intracellular mechanisms by which it affects the brain and body. Describe the many sites of action of alcohol in the central nervous system and its effects at each site (i.e., what receptors and other molecules does alcohol bind to, and what are the consequences of such binding on the brain and behavior). Describe the multiple mechanisms by which alcohol facilitates positive reinforcement.
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